SCIENCE

Study of the skin microbiome and the potential of topical probiotics in atopic dermatitis. Atopic dermatitis, also known as atopic eczema, is a chronic inflammatory skin disease that affects approximately 20% of children and 3% of adults in Western countries. The symptoms are mainly itching, red and dry skin and occur in periods of flare-ups. […]

Doctoral research at the faculty of Veterinary Medicine, UGent and the faculty of Bioengineering, UAntwerpen in collaboration with YUN N.V. The general aim of this research is to map the ear microbiome in the healthy dog, to evaluate the influence of CAD on this ear microbiome and to develop a topical ear product based on

Prof. Sarah Lebeer’s research team consists of a group of scientists who are fascinated by bacteria and their positive influence on our health. This multidisciplinary team consists of microbiologists, bioinformaticians and bioengineers and often works together with doctors, such as dermatologists, gynaecologists and general practitioners. They study the microbiome of humans, animals and plants and

Authors: Sarah Lebeer, Jos Vanderleyden, and Sigrid C. J. De Keersmaecker “Lactobacilli have been crucial for the production of fermented products for centuries. They are also members of the mutualistic microbiota present in the human gastrointestinal and urogenital tract. Recently, increasing attention has been given to their probiotic, health-promoting capacities. Many human intervention studies demonstrating

Authors: Sarah Lebeer, Jos Vanderleyden & Sigrid C. J. De Keersmaecker “How can probiotic bacteria transduce their health benefits to the host? Bacterial cell surface macromolecules are key factors in this beneficial microorganism–host crosstalk, as they can interact with host pattern recognition receptors (PRRs) of the gastrointestinal mucosa. In this Review, we highlight the documented

Authors: Lize Delanghe, Irina Spacova, Joke Van Malderen, Eline Oerlemans, Ingmar Claes, Sarah Lebeer “The human skin microbiota forms a key barrier against skin pathogens and is important in modulating immune responses. Recent studies identify lactobacilli as endogenous inhabitants of healthy skin, while inflammatory skin conditions are often associated with a disturbed skin microbiome. Consequently,

Authors: Gilbert Donders, Gert Bellen, Eline Oerlemans, Ingmar Claes, Kateryna Ruban, Tim Henkens, Filip Kiekens & Sarah Lebeer “In vitro studies suggest that certain probiotic bacterial strains have potential activity against opportunistic infections such as Candida. There are few in vivo trials using probiotics as a single treatment for acute Candida vulvovaginitis (CV). In this open-label, proof-of-concept study,