SCIENCE

WHAT IS ATOPIC ECZEMA, WHAT CAUSES IT AND HOW CAN IT BE TREATED?

WHAT IS ATOPIC ECZEMA? Atopic eczema, also called atopic dermatitis, is a chronic inflammatory skin disease that causes itching, redness and scaling. The skin is inherently dry and has an impaired barrier function, so allergens are able to get in and cause inflammation. The result? Severe itching that affects your sleep and quality of life. […]

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BAEKELAND RESEARCH PROJECT: BREAKING THE VICIOUS ATOPIC DERMATITIS CYCLE

Study of the skin microbiome and the potential of topical probiotics in atopic dermatitis. Atopic dermatitis, also known as atopic eczema, is a chronic inflammatory skin disease that affects approximately 20% of children and 3% of adults in Western countries. The symptoms are mainly itching, red and dry skin and occur in periods of flare-ups.

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LAB FOR APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Prof. Sarah Lebeer’s research team consists of a group of scientists who are fascinated by bacteria and their positive influence on our health. This multidisciplinary team consists of microbiologists, bioinformaticians and bioengineers and often works together with doctors, such as dermatologists, gynaecologists and general practitioners. They study the microbiome of humans, animals and plants and

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LACTOBACILLI SUPPORTING PROBIOTIC ACTION

Authors: Sarah Lebeer, Jos Vanderleyden, and Sigrid C. J. De Keersmaecker “Lactobacilli have been crucial for the production of fermented products for centuries. They are also members of the mutualistic microbiota present in the human gastrointestinal and urogenital tract. Recently, increasing attention has been given to their probiotic, health-promoting capacities. Many human intervention studies demonstrating

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HOST INTERACTIONS OF PROBIOTIC BACTERIAL SURFACE MOLECULES

Authors: Sarah Lebeer, Jos Vanderleyden & Sigrid C. J. De Keersmaecker “How can probiotic bacteria transduce their health benefits to the host? Bacterial cell surface macromolecules are key factors in this beneficial microorganism–host crosstalk, as they can interact with host pattern recognition receptors (PRRs) of the gastrointestinal mucosa. In this Review, we highlight the documented

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THE ROLE OF LACTOBACILLI IN INHIBITING SKIN PATHOGENS

Authors: Lize Delanghe, Irina Spacova, Joke Van Malderen, Eline Oerlemans, Ingmar Claes, Sarah Lebeer “The human skin microbiota forms a key barrier against skin pathogens and is important in modulating immune responses. Recent studies identify lactobacilli as endogenous inhabitants of healthy skin, while inflammatory skin conditions are often associated with a disturbed skin microbiome. Consequently,

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TOPICAL CREAM WITH LIVE LACTOBACILLI MODULATES THE SKIN MICROBIOME AND REDUCE ACNE SYMPTOMS

Authors: Sarah Lebeer, Eline Oerlemans, Ingmar Claes, Sander Wuyts, Tim Henkens, Irina Spacova, Marianne van den Broek, Ines Tuyaerts, Stijn Wittouck, Ilke De Boeck, Camille N. Allonsius, Filip Kiekens, Julien Lambert “The skin is home to an important part of our commensal microbiota, despite it being a cool, acidic and desiccated environment. Tailored microbiome modulation

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THE USE OF 3 SELECTED LACTOBACILLARY STRAINS IN VAGINAL PROBIOTIC GEL FOR THE TREATMENT OF ACUTE CANDIDA VAGINITIS: A PROOF-OF-CONCEPT STUDY

Authors: Gilbert Donders, Gert Bellen, Eline Oerlemans, Ingmar Claes, Kateryna Ruban, Tim Henkens, Filip Kiekens & Sarah Lebeer “In vitro studies suggest that certain probiotic bacterial strains have potential activity against opportunistic infections such as Candida. There are few in vivo trials using probiotics as a single treatment for acute Candida vulvovaginitis (CV). In this open-label, proof-of-concept study,

THE USE OF 3 SELECTED LACTOBACILLARY STRAINS IN VAGINAL PROBIOTIC GEL FOR THE TREATMENT OF ACUTE CANDIDA VAGINITIS: A PROOF-OF-CONCEPT STUDY Read More »