SCIENCE

Study of the skin microbiome and the potential of topical probiotics in atopic dermatitis. Atopic dermatitis, also known as atopic eczema, is a chronic inflammatory skin disease that affects approximately 20% of children and 3% of adults in Western countries. The symptoms are mainly itching, red and dry skin and occur in periods of flare-ups. …

BAEKELAND RESEARCH PROJECT: BREAKING THE VICIOUS ATOPIC DERMATITIS CYCLE Read More »

Prof. Sarah Lebeer’s research team consists of a group of scientists who are fascinated by bacteria and their positive influence on our health. This multidisciplinary team consists of microbiologists, bioinformaticians and bioengineers and often works together with doctors, such as dermatologists, gynaecologists and general practitioners. They study the microbiome of humans, animals and plants and …

LAB FOR APPLIED MICROBIOLOGY AND BIOTECHNOLOGY Read More »

Authors: Sarah Lebeer, Jos Vanderleyden, and Sigrid C. J. De Keersmaecker “Lactobacilli have been crucial for the production of fermented products for centuries. They are also members of the mutualistic microbiota present in the human gastrointestinal and urogenital tract. Recently, increasing attention has been given to their probiotic, health-promoting capacities. Many human intervention studies demonstrating …

LACTOBACILLI SUPPORTING PROBIOTIC ACTION Read More »

Authors: Lize Delanghe, Irina Spacova, Joke Van Malderen, Eline Oerlemans, Ingmar Claes, Sarah Lebeer “The human skin microbiota forms a key barrier against skin pathogens and is important in modulating immune responses. Recent studies identify lactobacilli as endogenous inhabitants of healthy skin, while inflammatory skin conditions are often associated with a disturbed skin microbiome. Consequently, …

THE ROLE OF LACTOBACILLI IN INHIBITING SKIN PATHOGENS Read More »

Authors: Sarah Lebeer, Eline Oerlemans, Ingmar Claes, Sander Wuyts, Tim Henkens, Irina Spacova, Marianne van den Broek, Ines Tuyaerts, Stijn Wittouck, Ilke De Boeck, Camille N. Allonsius, Filip Kiekens, Julien Lambert “The skin is home to an important part of our commensal microbiota, despite it being a cool, acidic and desiccated environment. Tailored microbiome modulation …

TOPICAL CREAM WITH LIVE LACTOBACILLI MODULATES THE SKIN MICROBIOME AND REDUCE ACNE SYMPTOMS Read More »

Authors: Gilbert Donders, Gert Bellen, Eline Oerlemans, Ingmar Claes, Kateryna Ruban, Tim Henkens, Filip Kiekens & Sarah Lebeer “In vitro studies suggest that certain probiotic bacterial strains have potential activity against opportunistic infections such as Candida. There are few in vivo trials using probiotics as a single treatment for acute Candida vulvovaginitis (CV). In this open-label, proof-of-concept study, …

THE USE OF 3 SELECTED LACTOBACILLARY STRAINS IN VAGINAL PROBIOTIC GEL FOR THE TREATMENT OF ACUTE CANDIDA VAGINITIS: A PROOF-OF-CONCEPT STUDY Read More »

Authors: Eline F. M. Oerlemans, Gert Bellen, Ingmar Claes, Tim Henkens, Camille Nina Allonsius, Stijn Wittouck, Marianne F. L. van den Broek, Sander Wuyts, Filip Kiekens, Gilbert G. G. Donders & Sarah Lebeer “Vulvovaginal candidosis (VVC) is a common condition with severe symptoms and high recurrence rates. Probiotic lactobacilli are explored as alternatives to azole …

IMPACT OF A LACTOBACILLI-CONTAINING GEL ON VULVOVAGINAL CANDIDOSIS AND THE VAGINAL MICROBIOME Read More »