A Study of the Skin Microbiome and the Potential of Topical Probiotics in Atopic Dermatitis
Atopic dermatitis usually begins early in childhood and is often the first condition in the so-called “atopic march,” a term that refers to the sequential development of atopic eczema, hay fever, and asthma. The causes of atopic dermatitis are highly complex; the onset and course of the disease are influenced by both genetic and immunological mechanisms as well as environmental factors. In addition, a change in the skin microbiome is often observed in these individuals, which may contribute to the worsening of symptoms.
The need for new, effective treatments
Current therapies are often ineffective or cause significant side effects. Therefore, alternative treatments are urgently needed. This project aims to explore the skin microbiome in atopic dermatitis and apply this knowledge to the development of a new probiotic product. Based on Prof. Lebeer’s research, probiotic bacteria show great potential for the treatment of atopic dermatitis. Previous experiments have shown that lactobacilli can compete with skin pathogens such as staphylococci. However, more in-depth research is needed before it can be proposed as a therapy. In this way, we aim to offer a sustainable solution through an effective probiotic therapy and relieve a large group of children and adults of their itching, dry skin, and sleepless nights.
